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Home / Primary Antibodies

T-bet Antibody (TBX21) (R31106)

SKU : BHA17104596

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NSJ Bioreagents

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Mfr.No.	R31106
Clonality	Polyclonal
Description	TBX21 (T-Box 21), also called T-bet (T-box expressed in T cells), is a protein that in humans is encoded by the TBX21 gene. This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. Zhang and Yang(2000) mapped the mouse Tbx21 gene to chromosome 11D in an area showing homology of synteny with human chromosome 17. Szabo et al.(2000) showed that expression correlates with IFNG expression in Th1 and natural killer(NK) cells. Ectopic expression of T-bet both transactivated the IFNG gene and induced endogenous IFNG production. Finotto et al.(2002) observed reduced expression of the T(H)1 transcription factor T-bet in T cells from airways of patients with asthma compared with that in T cells from airways of nonasthmatic patients, suggesting that loss might be associated with asthma.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An amino acid sequence from the C-terminus of human T-box expressed in T cells (DKEAEGQFYNYFPN) was used as the immunogen for this T-bet antibody.
Isotype	IgG
Predicted Reactivity	Human, Mouse, Rat
Reactivity	Human, Mouse, Rat
Recombinant	No

Uniprot	Q9UL17

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the T-bet antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB
Dilution	Weste blot: 0.5-1ug/ml

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17104596	R31106	100 ug	$419		Add to Cart

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