Covalent modification of target lysines by SUMO (small ubiquitin-like modifier) modulates processes such as protein localization, transcription, nuclear transport, mitosis, DNA replication and repair, signal transduction, and viral reproduction. SUMO does not seem to be involved in protein degradation and may in fact function as an antagonist of ubiquitin in the degradation process. In the development of Drosophila, SUMO plays a mateal role in anterior-posterior (A/P) polarity and patteing.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Host
Rabbit
Immunogen Region
This SUMO antibody was produced from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of Drosophila SUMO1.
Isotype
Ig
Predicted Reactivity
Human, Drosophila
Reactivity
Human, Drosophila
Recombinant
No
Uniprot
O97102
Format
Purified
Purification
Purified
Storage
Aliquot the SUMO antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.