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Home / Primary Antibodies / Polyclonal Antibodies

STI1P (HOP) Antibody - SPC-203

BHA11907395
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Email
[email protected]
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Swissprot P15705
Accession Number NP_014670.1
Gene Id 854192
Target HOP
Research Area Cancer, Heat Shock, Cell Signaling, Chaperone Proteins, Protein Trafficking
Buffer Rabbit Antiserum, PBS, 50% glycerol
Dilutions WB (1:2500); optimal dilutions for assays should be determined by the user.
Purification Rabbit Antiserum
Scientific Background The stress inducible protein Sti1p is also commonly known as HSP70-HSP90 organization protein (HOP). It is located in diverse cellular regions and can move between the cytoplasm and the nucleus. It functions to reversibly link together the protein chaperones HSP70 and HSP90. HOP contains three tetratricopeptide repeat (TPR) domains, TPR1, TPR2a and TPR2b. HSP70 binding has been localized to TRP1 and sp90 binding have been localized to TPR2a (1). It has also been found to modulate the chaperone activities of the linked proteins and possible interacts with other chaperones and proteins. It has also been found to participate in other complexes besides the HSP70/HSP90 one (2). HOP is closely related to human 63kDa protein that is sensitive to simian virus SV40 transformation, and is related to the yeast heat-shock- responsive STI1 gene product (3, 4).
Shipping Temperature Blue Ice or 4°C
Specificity Detects ~ 66kDa.
Storage -20ºC
Storage Buffer Rabbit Antiserum, PBS, 50% glycerol, *Storage buffer may change when conjugated
Storage Temperature -20°C
Applications ELISA, WB, FCM
Description WB ; ELISA ; FCM
Dilution WB (1:2500); optimal dilutions for assays should be determined by the user.
Product Manual SDS
SDS
Reference 1. Flom G., Behal R.H., Rosen L., Cole D.G., Johnson J.L. (2007) Biochem J. 404(1): 159-167.

2. Harst A., Lin H., Obermann W.M. (2005) Biochem J. 387 (pt3): 789-796.

3. Honore B.H., et al. (1992) J Biol Chem. 267: 8485- 8491.

4. Nicolet C.M., et al. (1989) Mol Cell Bio. 9: 3638-3646.
Combination SKU Supplier No. Conjugate Size Your price Quantity
BHA11907395-1 SPC-203D Unconjugated 100 ul $306
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BHA11907395-2 SPC-203D-A390 ATTO 390 100 ul $360
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BHA11907395-3 SPC-203D-A488 ATTO 488 100 ul $359
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BHA11907395-4 SPC-203D-A594 ATTO 594 100 ul $359
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BHA11907395-5 SPC-203D-ALP Alkaline Phosphatase 100 ul $352
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BHA11907395-6 SPC-203D-APC APC 100 ul $358
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BHA11907395-7 SPC-203D-BI Biotin 100 ul $354
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BHA11907395-8 SPC-203D-FITC FITC 100 ul $350
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BHA11907395-9 SPC-203D-HRP HRP 100 ul $345
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BHA11907395-10 SPC-203D-PCP PerCP 100 ul $358
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BHA11907395-11 SPC-203D-RPE RPE 100 ul $355
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