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Home / Antibodies

STAT5A Antibody

SKU : BHA10557853

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA052847
Alternative Names	MGF; MPF; Mammary gland factor; STA5A; STAT5
Categories	Primary Antibodies
Clonality	polyclonal
Description	Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation.Hou J., Immunity 2:321-329(1995).Litterst C.M., J. Biol. Chem. 278:45340-45351(2003).Martens N., J. Biol. Chem. 280:13817-13823(2005).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human STAT5A.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation. Hou J., Immunity 2:321-329(1995). Litterst C.M., J. Biol. Chem. 278:45340-45351(2003). Martens N., J. Biol. Chem. 280:13817-13823(2005).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total STAT5A protein.
Subcellular Location	Cytoplasm, Nucleus

Uniprot	P42229
Database Links	HGNC:11366 OMIM:601511 KEGG:hsa:6776 STRING:9606.ENSP00000341208 UniGene:Hs.437058
Function	Carries out a dual function
Pathway	ErbB signaling pathway Jak-STAT signaling pathway Necroptosis Th1 and Th2 cell differentiation Th17 cell differentiation AGE-RAGE signaling pathway in diabetic complications
Protein Families	Transcription factor STAT family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557853	CSB-PA052847	100ul	$297		Add to Cart

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