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Home / Primary Antibodies

Stat5 (phospho Tyr694/699) Polyclonal Antibody

SKU : BHA13706978

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Abbkine Scientific Co., Ltd.

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Mfr.No.	ABP56301
Alternative Names	STAT5A; STAT5; Signal transducer and activator of transcription 5A; STAT5B; Signal transducer and activator of transcription 5B
Background	The protein encoded by STAT5A (signal transducer and activator of transcription 5A) is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of STAT5A is found to induce the expression of BCL2L1/BCL-X (L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been found for STAT5A.
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	Polyclonal
Description	Rabbit Anti-Stat5 (phospho Tyr694/699) Polyclonal Antibody
Formulation	Liquid solution
Host	Rabbit
Immunogen	Synthesized peptide derived from human Stat5 around the phosphorylation site of Y694/699
Immunogen Region	Synthesized peptide derived from human Stat5 around the phosphorylation site of Y694/699
Isotype	Rabbit IgG
Others	Phospho-Stat5 (Y694/699) Polyclonal Antibody detects endogenous levels of Stat5 protein only when phosphorylated at Y694/699. Observed Band (KD): 91
Precautions	The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Reactivity	Human, Mouse, Rat
Shipping	Gel pack with blue ice.
Tag	Signal transducer and activator of transcription 5A
Note	Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Accession Number	P42229/P51692
Gene Id	6776/6777

Concentration	1 mg/ml
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Storage Buffer	PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instructions	Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Applications	ELISA, IHC-P, WB
Dilution	Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Product Manual	Datasheet
Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA13706978	ABP56301	30 uL	$109		Add to Cart
BHA13706978	ABP56301	100 uL	$239		Add to Cart
BHA13706978	ABP56301	200 uL	$379		Add to Cart

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