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Home / Primary Antibodies

STAT3 Antibody (phospho-S727) (F48455)

SKU : BHA17101231

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NSJ Bioreagents

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Mfr.No.	F48455, F48455-0.08ML, F48455-0.4ML
Antigen	p-STAT3
Clonality	Polyclonal
Description	STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. It mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein.
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	This p-STAT3 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS727 of human STAT3.
Isotype	Ig
Predicted Reactivity	Human, Mouse
Reactivity	Human, Mouse
Recombinant	No

Uniprot	P40763

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	Aliquot the p-STAT3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	IF, WB, IHC, ELISA
Dilution	Immunofluorescence: 1:200,Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17101231-1	F48455-0.08ML	0.08ml	$165		Add to Cart
BHA17101231-2	F48455-0.4ML	0.4ml	$379		Add to Cart

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