STA13; START domain containing 13; START domain- containing protein 13; StAR-related lipid transfer protein 13; deleted in liver cancer 2
Categories
Primary Antibodies
Clonality
polyclonal
Description
GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells.Ching Y.-P., J. Biol. Chem. 278:10824-10830(2003).Nagaraja G.M., Biochem. Biophys. Res. Commun. 313:654-665(2004).Leung T.H.-Y., Proc. Natl. Acad. Sci. U.S.A. 102:15207-15212(2005).
Host
Rabbit
Immunogen
Synthesized peptide derived from N-terminal of Human STA13.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells.
GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells.
Tissue Specificity
Ubiquitously expressed. Underexpressed in hepatocellular carcinoma cells and some breast cancer cell lines.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.