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Home / Antibodies

STAG3 Antibody

SKU : BHA10558054

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA167892
Alternative Names	Cohesin subunit SA-3; Stromal antigen 3; Stromalin 3; SCC3 homolog 3; STAG3
Categories	Primary Antibodies
Clonality	polyclonal
Description	Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I By similarity.Pezzi N., FASEB J. 14:581-592(2000).The German cDNA consortium; Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.Prieto I., EMBO Rep. 3:543-550(2002).
Host	Rabbit
Immunogen	Synthesized peptide derived from C-terminal of Human STAG3.
Involvement In Disease	Premature ovarian failure 8 (POF8)
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I By similarity. Pezzi N., FASEB J. 14:581-592(2000). The German cDNA consortium; Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases. Prieto I., EMBO Rep. 3:543-550(2002).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total STAG3 protein.
Subcellular Location	Nucleus, Chromosome, Chromosome, centromere

Uniprot	Q9UJ98
Database Links	HGNC:11356 OMIM:608489 KEGG:hsa:10734 STRING:9606.ENSP00000319318 UniGene:Hs.592283
Function	Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I.
Protein Families	SCC3 family
Tissue Specificity	Testis specific.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558054	CSB-PA167892	100ul	$297		Add to Cart

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