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Home / Antibodies

SPTBN2 Antibody / Spectrin beta III (V7519)

SKU : BHA17116438

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NSJ Bioreagents

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Mfr.No.	V7519, V7519-20UG, V7519-100UG
Antigen	SPTBN2
Clonality	Monoclonal
Description	Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II), four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin and spectrin are present in erythrocytes, whereas spectrin II (also designated fodrin ) and spectrin I (also designated fodrin ) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrin III is highly homologous to both spectrin I and spectrin II. Spectrin III is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta.
Formulation	0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Host	Rabbit
Immunogen Region	Human recombinant partial protein corresponding to amino acids 356-475 was used as the immunogen for this recombinant Spectrin beta III antibody.
Isotype	IgG,kappa
Predicted Reactivity	Human
Reactivity	Human
Recombinant	Yes
Subcellular Location	Cell surface, cytoplasm

Uniprot	O15020
Clone No	SPTBN2/3142R

Concentration	0.2 mg/ml
Format	Purified
Purification	Protein A affinity chromatography
Storage	Store the recombinant Spectrin beta III antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Applications	FACS IF, ELISA, WB, IHC-P
Dilution	ELISA: 2-4ug/ml (order BSA/azide-free format),Western blot: 1-2ug/ml,Flow cytometry: 0.5-1ug/million cells Immunofluorescence: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17116438-1	V7519-20UG	20ug	$219		Add to Cart
BHA17116438-2	V7519-100UG	100ug	$499		Add to Cart

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