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Home / Antibodies

SPTBN2 Antibody / Spectrin beta III (V7447SAF)

SKU : BHA17126512

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NSJ Bioreagents

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Mfr.No.	V7447SAF-100UG
Clonality	Recombinant Rabbit Monoclonal
Description	Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. (RefSeq)
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Rabbit
Immunogen Region	Amino acids 356-475 from the human protein were used as the immunogen for this recombinant SPTBN2 antibody.
Isotype	Rabbit IgG, kappa
Species Reactivity	Human
Note	Optimal dilution of the recombinant SPTBN2 antibody should be determined by the researcher.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Uniprot	O15020

Format	Purified
Purity	Protein A affinity chromatography
Storage	Store the recombinant SPTBN2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	IHC-P, FACS, WB
Description	Weste blot: 1-2ug/ml,Flow cytometry: 1-2ug/million cells in 0.1ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/recombinant-sptbn2-antibody-scnb3-2r-v7447" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17126512	V7447SAF-100UG	100 ug	$499		Add to Cart

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