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Home / Antibodies

SPP1 Antibody

SKU : BHA10559201

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA827743
Alternative Names	Bone sialoprotein 1; Nephropontin; OPN; OSTP; SPP-1
Categories	Primary Antibodies
Clonality	polyclonal
Description	Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction.Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity By similarity.George R. Beck, J. Biol. Chem., Oct 2003; 278: 41921 - 41929. KELLY L. HUDKINS, J. Am. Soc. Nephrol., Mar 1999; 10: 444. L篓鐚ia R. Rodrigues, Cancer Epidemiol. Biomarkers Prev., Jun 2007; 16: 1087 - 1097. Yu-Hua Hsieh, Cancer Res., Jul 2006; 66: 7119 -
Host	Rabbit
Immunogen	Synthesized peptide derived from Human osteopontin .
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction.Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity By similarity. George R. Beck, J. Biol. Chem., Oct 2003; 278: 41921 - 41929. KELLY L. HUDKINS, J. Am. Soc. Nephrol., Mar 1999; 10: 444. L?a R. Rodrigues, Cancer Epidemiol. Biomarkers Prev., Jun 2007; 16: 1087 - 1097. Yu-Hua Hsieh, Cancer Res., Jul 2006; 66: 7119 -
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total osteopontin protein.
Subcellular Location	Secreted

Uniprot	P10451
Database Links	HGNC:11255 OMIM:166490 KEGG:hsa:6696 STRING:9606.ENSP00000378517 UniGene:Hs.313
Function	Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction.; FUNCTION
Pathway	PI3K-Akt signaling pathway Focal adhesion Toll-like receptor signaling pathway Apelin signaling pathway
Protein Families	Osteopontin family
Tissue Specificity	Bone. Found in plasma.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559201	CSB-PA827743	100ul	$297		Add to Cart

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