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Home / Primary Antibodies

SPIC Antibody

SKU : BHA10557971

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA439876
Alternative Names	Transcription factor Spi-C; SPIC;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression By similarity.Carlsson R., Gene 299:271-278(2002).The MGC Project Team, Genome Res. 14:2121-2127(2004).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human SPIC.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression By similarity. Carlsson R., Gene 299:271-278(2002). The MGC Project Team, Genome Res. 14:2121-2127(2004).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total SPIC protein.
Subcellular Location	Nucleus

Uniprot	Q8N5J4
Database Links	HGNC:29549 OMIM:612568 KEGG:hsa:121599 STRING:9606.ENSP00000299272 UniGene:Hs.577097
Function	Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression (By similarity).
Protein Families	ETS family
Tissue Specificity	Preferentially detected in fetal and adult spleen, lymph nodes and at lower levels in bone marrow and fetal liver.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557971	CSB-PA439876	100ul	$297		Add to Cart

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