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Home / Antibodies

SPI1 Antibody

SKU : BHA10557815

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA580989
Alternative Names	31 kDa transforming protein; SPI1; transcription factor PU.1;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing By similarity.Ray D., Oncogene 5:663-668(1990).Rao S., J. Biol. Chem. 274:11115-11124(1999).Mao S., Mol. Cell. Biol. 19:3635-3644(1999).
Host	Rabbit
Immunogen	Synthesized peptide derived from inteal of Human SPI1.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing By similarity. Ray D., Oncogene 5:663-668(1990). Rao S., J. Biol. Chem. 274:11115-11124(1999). Mao S., Mol. Cell. Biol. 19:3635-3644(1999).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total SPI1 protein.
Subcellular Location	Nucleus

Uniprot	P17947
Database Links	HGNC:11241 OMIM:165170 KEGG:hsa:6688 STRING:9606.ENSP00000227163 UniGene:Hs.502511
Function	Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing (By similarity).
Pathway	Osteoclast differentiation
Protein Families	ETS family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557815	CSB-PA580989	100ul	$297		Add to Cart

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