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Home / Primary Antibodies

SP3/SP4 Antibody

SKU : BHA10557895

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA081786
Alternative Names	LAG1 longevity assurance; SP260; TMSG1; Tumor metastasis-suppressor gene 1 protein;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcriptional factor that can act as an activator or repressor depending on isoform and/orpost-translational modifications. Binds to GT and GC boxes promoter elements. Competes with SP1 for the GC-box promoters. Weak activator of transcription but can activate a number of genes involved in different processes such as cell-cycle regulation, hormone-induction and house-keeping.Pan H., Genomics 77:58-64(2001).The MGC Project Team, Genome Res. 14:2121-2127(2004).Ota T., Nat. Genet. 36:40-45(2004).
Host	Rabbit
Immunogen	Synthesized peptide derived from C-terminal of Human SP3/4.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Transcriptional factor that can act as an activator or repressor depending on isoform and/orpost-translational modifications. Binds to GT and GC boxes promoter elements. Competes with SP1 for the GC-box promoters. Weak activator of transcription but can activate a number of genes involved in different processes such as cell-cycle regulation, hormone-induction and house-keeping. Pan H., Genomics 77:58-64(2001). The MGC Project Team, Genome Res. 14:2121-2127(2004). Ota T., Nat. Genet. 36:40-45(2004).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total SP3/4 protein.
Subcellular Location	Nucleus, Nucleus, PML body

Uniprot	Q02447
Database Links	HGNC:11208 OMIM:601804 KEGG:hsa:6670 STRING:9606.ENSP00000310301 UniGene:Hs.531587
Function	Transcriptional factor that can act as an activator or repressor depending on isoform and/or post-translational modifications. Binds to GT and GC boxes promoter elements. Competes with SP1 for the GC-box promoters. Weak activator of transcription but can activate a number of genes involved in different processes such as cell-cycle regulation, hormone-induction and house-keeping.
Protein Families	Sp1 C2H2-type zinc-finger protein family
Tissue Specificity	Ubiquitously expressed.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557895	CSB-PA081786	100ul	$297		Add to Cart

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