May be involved in several stages of intracellular trafficking. Plays a role in recycling endocytosed transferrin receptor and prevent its degradation.Haft C.R., Mol. Cell. Biol. 18:7278-7287(1998).Ota T., Nat. Genet. 36:40-45(2004).Mural R.J., Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human SNX4.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
May be involved in several stages of intracellular trafficking. Plays a role in recycling endocytosed transferrin receptor and prevent its degradation.
Haft C.R., Mol. Cell. Biol. 18:7278-7287(1998). Ota T., Nat. Genet. 36:40-45(2004). Mural R.J., Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total SNX4 protein.
Subcellular Location
Early endosome membrane, Peripheral membrane protein, Cytoplasmic side
May be involved in several stages of intracellular trafficking. Plays a role in recycling endocytosed transferrin receptor and prevent its degradation.
Pathway
Endocytosis
Protein Families
Sorting nexin family
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.