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Home / Primary Antibodies

SLC5A8 Antibody / Sodium-coupled monocarboxylate transporter 1 (F53928)

SKU : BHA17102534

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Mfr.No.	F53928, F53928-0.05ML, F53928-0.2ML
Antigen	SLC5A8
Clonality	Polyclonal
Description	Solute carrier family 5 member 8 acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D- hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1. Catalyzes passive carrier mediated diffusion of iodide. Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane. May be responsible for the absorption of D- lactate and monocarboxylate drugs from the intestinal tract. Acts as a tumor suppressor, suppressing colony formation in colon cancer, prostate cancer and glioma cell lines. May play a critical role in the entry of L-lactate and ketone bodies into neurons by a process driven by an electrochemical Na(+) gradient and hence contribute to the maintenance of the energy status and function of neurons.
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	A portion of amino acids 579-609 from the human protein was used as the immunogen for the SLC5A8 antibody.
Isotype	Ig
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	Q8N695
Gene Id	160728

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	Aliquot the SLC5A8 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	WB
Dilution	Western blot: 1:500-1000

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17102534-1	F53928-0.05ML	0.05ml	$165		Add to Cart
BHA17102534-2	F53928-0.2ML	0.2ml	$379		Add to Cart

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