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Home / Antibodies

SLC27A4 Antibody

SKU : BHA10558464

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA193776
Alternative Names	Long-chain fatty acid transport protein 4; EC 6.2.1.-; Fatty acid transport protein 4; FATP-4; Solute carrier family 27 member 4
Categories	Primary Antibodies
Clonality	polyclonal
Description	Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Appears to be the principal fatty acid transporter in small intestinal enterocytes. Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (VLCFAs). Indirectly inhibits RPE65 via substrate competition and via production of VLCFA derivatives like lignoceroyl-CoA. Prevents light-induced degeneration of rods and cones By similarity.Fitscher B.A., Biochim. Biophys. Acta 1443:381-385(1998).Humphray S.J., Nature 429:369-374(2004).Colinge J., Submitted (OCT-2008) to UniProtKB.
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human SLC27A4.
Involvement In Disease	Ichthyosis prematurity syndrome (IPS)
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Appears to be the principal fatty acid transporter in small intestinal enterocytes. Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (VLCFAs). Indirectly inhibits RPE65 via substrate competition and via production of VLCFA derivatives like lignoceroyl-CoA. Prevents light-induced degeneration of rods and cones By similarity. Fitscher B.A., Biochim. Biophys. Acta 1443:381-385(1998). Humphray S.J., Nature 429:369-374(2004). Colinge J., Submitted (OCT-2008) to UniProtKB.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total SLC27A4 protein.
Subcellular Location	Membrane, Multi-pass membrane protein, Endoplasmic reticulum membrane

Uniprot	Q6P1M0
Gene Id	10999
Database Links	HGNC:10998 OMIM:604194 KEGG:hsa:10999 STRING:9606.ENSP00000300456 UniGene:Hs.656699
Function	Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Appears to be the principal fatty acid transporter in small intestinal enterocytes. Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (VLCFAs). Indirectly inhibits RPE65 via substrate competition and via production of VLCFA derivatives like lignoceroyl-CoA. Prevents light-induced degeneration of rods and cones (By similarity).
Pathway	PPAR signaling pathway
Protein Families	ATP-dependent AMP-binding enzyme family
Tissue Specificity	Expressed at highest levels in brain, testis, colon and kidney. Expressed at medium levels in heart and liver, small intestine and stomach. Expressed at low levels in peripheral leukocytes, bone marrow, skeletal muscle and aorta. Expressed in adipose tiss
Weight	26,001 Da

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, IF

Description

ELISA ; IF, IF ; ELISA

Dilution

IF	1:100-1:500

Tested Application

ELISA,IF;IF:1:100-1:500

Datasheet
ELISA Protocol
Immunofluorescence (IF) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558464	CSB-PA193776	100ul	$297		Add to Cart

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