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Home / Antibodies

SIRT3 Antibody

SKU : BHA10558805

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA229200
Alternative Names	NAD-dependent deacetylase sirtuin-3; mitochondrial; SIR2-like protein 3; hSIRT3; SIRT3
Categories	Primary Antibodies
Clonality	polyclonal
Description	NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA and the ATP synthase subunit ATP5O. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.Bechtel S., BMC Genomics 8:399-399(2007).Schwer B., J. Cell Biol. 158:647-657(2002).Onyango P., Proc. Natl. Acad. Sci. U.S.A. 99:13653-13658(2002).
Host	Rabbit
Immunogen	Synthesized peptide derived from C-terminal of Human SIRT3.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA and the ATP synthase subunit ATP5O. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels. Bechtel S., BMC Genomics 8:399-399(2007). Schwer B., J. Cell Biol. 158:647-657(2002). Onyango P., Proc. Natl. Acad. Sci. U.S.A. 99:13653-13658(2002).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total SIRT3 protein.
Subcellular Location	Mitochondrion matrix

Uniprot	Q9NTG7
Database Links	HGNC:14931 OMIM:604481 KEGG:hsa:23410 STRING:9606.ENSP00000372191 UniGene:Hs.716456
Function	NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA and the ATP synthase subunit ATP5O. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.
Protein Families	Sirtuin family, Class I subfamily
Tissue Specificity	Widely expressed.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558805	CSB-PA229200	100ul	$297		Add to Cart

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