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Home / Primary Antibodies

SHP2 Antibody (F53772)

SKU : BHA17119863

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NSJ Bioreagents

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Mfr.No.	F53772-0.4ML
Clonality	Polyclonal (rabbit origin)
Description	SHP2, also known as PTPN11, is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in the gene are a cause of Noonan syndrome as well as acute myeloid leukemia.
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	A portion of amino acids 526-551 from the human protein was used as the immunogen for this SHP2 antibody.
Isotype	Rabbit Ig
Species Reactivity	Human
Note	Titration of the SHP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Uniprot	Q06124

Format	Antigen affinity purified
Purity	Antigen affinity
Storage	Aliquot the SHP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC, FACS, ELISA
Description	Weste blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17119863	F53772-0.4ML	0.4 ml	$379		Add to Cart

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