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Home / Primary Antibodies

SHP2 Antibody

SKU : BHA17102404

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NSJ Bioreagents

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Mfr.No.	F53772
Clonality	Polyclonal
Description	SHP2, also known as PTPN11, is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in the gene are a cause of Noonan syndrome as well as acute myeloid leukemia.
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	A portion of amino acids 526-551 from the human protein was used as the immunogen for this SHP2 antibody.
Isotype	Ig
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	Q06124

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	Aliquot the SHP2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC, FACS, ELISA
Dilution	Weste blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17102404	F53772	0.4 ml	$379		Add to Cart

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