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Home / Primary Antibodies

SHBG Antibody (R31739)

SKU : BHA17105106

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NSJ Bioreagents

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Mfr.No.	R31739
Clonality	Polyclonal
Description	Sex hormone-binding globulin (SHBG) is a glycoprotein that binds to the sex hormones androgen and estrogen. SHBG is produced mostly by the liver and is released into the bloodstream. Other sites that produce it include the brain, uterus, testes, and placenta. It has both enhancing and inhibiting hormonal influences. It decreases with high levels of insulin, growth hormone, insulin-like growth factor 1 (IGF-1), androgens, prolactin and transcortin. High estrogen, andthyroxine cause it to increase. It has been found that the monosaccharides glucose and fructose reduced human SHBG production by hepatocytes, irrespective of the presence of insulin, by downregulation of hepatocyte nuclear factor-4A and replacement of HNF4A by COUP-TFI at a cis-element within the human SHBG promoter, coincident with repression of its transcriptional activity.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Human partial recombinant protein (AA 30-210) was used as the immunogen for this SHBG antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Gene Id	6462

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the SHBG antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB
Dilution	Weste blot: 0.5-1ug/ml

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17105106	R31739	100 ug	$419		Add to Cart

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