Serum/glucocorticoid-regulated kinase 1 is a serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cellular enzymes, transcription factors, neuronal excitability, cell growth, proliferation, survival, migration and apoptosis. Plays an important role in cellular stress response. Contributes to regulation of renal Na(+) retention, renal K(+) elimination, salt appetite, gastric acid secretion, intestinal Na(+)/H(+) exchange and nutrient transport, insulin-dependent salt sensitivity of blood pressure, salt sensitivity of peripheral glucose uptake, cardiac repolarization and memory consolidation.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Host
Rabbit
Immunogen Region
The amino acids surrounding serine 78 of human Serum/glucocorticoid-regulated kinase 1 were used as the immunogen for the SGK1 antibody.
Isotype
Ig
Predicted Reactivity
Human
Reactivity
Human
Recombinant
No
Uniprot
O00141
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
Aliquot the SGK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.