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Home / Primary Antibodies

SF3B6 Antibody

SKU : BHA10558592

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA201433
Alternative Names	CGI-110; HSPC175; Ht006; PM14; pre-mRNA branch site protein p14
Categories	Primary Antibodies
Clonality	polyclonal
Description	Necessary for the splicing of pre-mRNA. Directly contacts the pre-mRNA branch site adenosine for the first catalytic step of splicing. Enters the spliceosome and associates with the pre-mRNA branch site as part of the 17S U2 or, in the case of the minor spliceosome, as part of the 18S U11/U12 snRNP complex, and thus may facilitate the interaction of these snRNP with the branch sites of U2 and U12 respectively.Will C.L., EMBO J. 20:4536-4546(2001).Lai C.-H., Genome Res. 10:703-713(2000).Zhang Q.-H., Genome Res. 10:1546-1560(2000).
Host	Rabbit
Immunogen	Synthesized peptide derived from C-terminal of Human SF3B14.
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Necessary for the splicing of pre-mRNA. Directly contacts the pre-mRNA branch site adenosine for the first catalytic step of splicing. Enters the spliceosome and associates with the pre-mRNA branch site as part of the 17S U2 or, in the case of the minor spliceosome, as part of the 18S U11/U12 snRNP complex, and thus may facilitate the interaction of these snRNP with the branch sites of U2 and U12 respectively. Will C.L., EMBO J. 20:4536-4546(2001). Lai C.-H., Genome Res. 10:703-713(2000). Zhang Q.-H., Genome Res. 10:1546-1560(2000).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total SF3B14 protein.
Subcellular Location	Nucleus

Uniprot	Q9Y3B4
Database Links	HGNC:30096 OMIM:607835 KEGG:hsa:51639 STRING:9606.ENSP00000233468 UniGene:Hs.177861
Function	Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex
Protein Families	SF3B6 family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558592	CSB-PA201433	100ul	$297		Add to Cart

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