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Home / Antibodies

SERPINI1 Antibody

SKU : BHA10557567

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA869434
Alternative Names	PI12; SERPINI1;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.Davis R.L., Shrimpton A.E., Holohan P.D. Nature 401:376-379(1999)
Host	Rabbit
Immunogen	Peptide sequence around aa.402~406(T-S-G-H-D) derived from Human Neuroserpin.
Involvement In Disease	Encephalopathy, familial, with neuroserpin inclusion bodies (FENIB)
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator. Davis R.L., Shrimpton A.E., Holohan P.D. Nature 401:376-379(1999)
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous level of total Neuroserpin protein.
Subcellular Location	Secreted, Cytoplasmic vesicle, secretory vesicle lumen, Perikaryon

Uniprot	Q99574
Database Links	HGNC:8943 OMIM:602445 KEGG:hsa:5274 STRING:9606.ENSP00000295777 UniGene:Hs.478153
Function	Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin
Protein Families	Serpin family
Tissue Specificity	Detected in brain cortex and hippocampus pyramidal neurons (at protein level) (PubMed:17040209). Predominantly expressed in the brain (PubMed:9070919).

Buffer	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Purity	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:1000

Tested Application

ELISA,WB;WB:1:500-1:1000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557567	CSB-PA869434	100ul	$297		Add to Cart

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