SERPINB2 is also known as PAI or PAI2. It is a coagulation factor that inactivates tPA and Urokinase. It is present in most cells, especially monocytes/macrophages. The protein exists in two forms, a 60-kDa extracellular glycosylated form and a 43-kDa intracellular form. It is present only at detectable quantities in blood during pregnancy, as it is produced by the placenta, and may explain partially the increased rate of thrombosisduring pregnancy. The majority of expressed SERPINB2 remains unsecreted due to the presence of an inefficient internal signal peptide.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
Human partial recombinant protein (AA 1-180) was used as the immunogen for this SERPINB2 antibody.
Isotype
IgG
Predicted Reactivity
Human
Reactivity
Human
Recombinant
No
Gene Id
5055
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
After reconstitution, the SERPINB2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Applications
WB, IHC-P
Dilution
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml