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Home / Antibodies

SCNN1D Antibody

SKU : BHA10559452

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA989132
Alternative Names	Amiloride-sensitive sodium channel subunit delta; Epithelial Na(+) channel subunit delta; Delta-ENaC; SCNED; Nonvoltage-gated sodium channel 1 subunit delta
Categories	Primary Antibodies
Clonality	polyclonal
Description	Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.Waldmann R., J. Biol. Chem. 270:27411-27414(1995).Ota T., Nat. Genet. 36:40-45(2004).Gregory S.G., Nature 441:315-321(2006).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human SCNN1D.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. Waldmann R., J. Biol. Chem. 270:27411-27414(1995). Ota T., Nat. Genet. 36:40-45(2004). Gregory S.G., Nature 441:315-321(2006).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total SCNN1D protein.
Subcellular Location	Cell membrane, Multi-pass membrane protein

Uniprot	P51172
Database Links	HGNC:10601 OMIM:601328 KEGG:hsa:6339 STRING:9606.ENSP00000368411 UniGene:Hs.512681
Function	Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
Protein Families	Amiloride-sensitive sodium channel (TC 1.A.6) family, SCNN1D subfamily

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IF

Description

ELISA ; WB ; IF, WB ; ELISA ; IF

Dilution

WB	1:500-1:3000
IF	1:100-1:500

Tested Application

ELISA,WB,IF;WB:1:500-1:3000,IF:1:100-1:500

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10559452	CSB-PA989132	100ul	$297		Add to Cart

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