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Home / Primary Antibodies

SCN7A Antibody

SKU : BHA10558691

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA779166
Alternative Names	Sodium channel protein type 7 subunit alpha; Sodium channel protein type VII subunit alpha; Putative voltage-gated sodium channel subunit alpha Nax; Sodium channel protein cardiac and skeletal muscle subunit alpha; SCN7A
Categories	Primary Antibodies
Clonality	polyclonal
Description	Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient.George A.L. Jr., Proc. Natl. Acad. Sci. U.S.A. 89:4893-4897(1992).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human SCN7A.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient. George A.L. Jr., Proc. Natl. Acad. Sci. U.S.A. 89:4893-4897(1992).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total SCN7A protein.
Subcellular Location	Cell membrane, Multi-pass membrane protein

Uniprot	Q01118
Database Links	HGNC:10594 OMIM:182392 KEGG:hsa:6332 STRING:9606.ENSP00000386796 UniGene:Hs.596087
Function	Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
Protein Families	Sodium channel (TC 1.A.1.10) family, SCN7A subfamily
Tissue Specificity	Heart and uterus.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, IF

Description

ELISA ; IF, IF ; ELISA

Dilution

IF	1:100-1:500

Tested Application

ELISA,IF;IF:1:100-1:500

Datasheet
ELISA Protocol
Immunofluorescence (IF) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558691	CSB-PA779166	100ul	$297		Add to Cart

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