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Home / Antibodies

SATB2 Antibody (V8660SAF)

SKU : BHA17127672

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NSJ Bioreagents

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Mfr.No.	V8660SAF-100UG
Clonality	Recombinant Rabbit Monoclonal
Description	SATB2 (Special AT-rich sequence-binding protein 2) is a DNA binding protein that specifically binds nuclear matrix attachment regions. It is involved in transcription regulation and chromatin remodeling. SATB2 expression in colorectal carcinomas (CRC) is correlated with good prognosis and in laryngeal squamous cell carcinoma it functions as a tumor suppressor wherein loss of expression is positively correlated with high tumor grade and recurrence. Moreover, SATB2, in combination with CK20, could identify almost all CRC s. Upper gastrointestinal (GI) carcinomas and pancreatic ductal carcinomas are usually negative for SATB2, and ovarian carcinomas, lung adenocarcinomas, and adenocarcinomas from other origin are rarely positive for SATB2. Additionally, SATB2 antibody can identify neuroendocrine neoplasms of colon and rectum because SATB2 is usually negative in neuroendocrine neoplasms of the GI tract, pancreas, and lung. More recently, it has been reported that SATB2 is a sensitive marker for tumors with osteoblastic differentiation.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Rabbit
Immunogen Region	A portion of amino acids 200-300 from the human protein was used as the immunogen for the recombinant SATB2 antibody.
Isotype	Rabbit IgG
Species Reactivity	Human
Note	Optimal dilution of the recombinant SATB2 antibody should be determined by the researcher.

Uniprot	Q9UPW6

Format	Purified
Purity	Protein A affinity chromatography
Storage	Store the recombinant SATB2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	IHC-P
Description	Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/recombinant-satb2-antibody-satb2-4374r-v8660" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17127672	V8660SAF-100UG	100 ug	$499		Add to Cart

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