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Home / Antibodies

S100B Antibody (F54011)

SKU : BHA17119910

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NSJ Bioreagents

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Mfr.No.	F54011-0.1ML
Clonality	Monoclonal (mouse origin)
Description	Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
Formulation	Antibody in PBS with 50% Glycerol and 0.03% ProClin 300
Host	Mouse
Immunogen Region	A S100B synthetic peptide was used as the immunogen for this S100 beta antibody.
Isotype	Mouse lgG2b
Species Reactivity	Rat
Note	The stated application concentrations are suggested starting points. Titration of the S100 beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Uniprot	P04271

Format	Purified
Purity	Protein G affinity
Storage	Store the S100 beta antibody at -20oC.

Applications	WB
Description	Weste blot: 1:500

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17119910	F54011-0.1ML	0.1 ml	$379		Add to Cart

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