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Home / Primary Antibodies

S100B Antibody Cocktail (V3423)

SKU : BHA17113950

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NSJ Bioreagents

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Mfr.No.	V3423, V3423-20UG, V3423-100UG
Antigen	S100B
Clonality	Monoclonal
Description	S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the beta-chain (i.e. in S-100A and S-100B) but not on the alpha-chain of S-100 (i.e. in S-100A and S100A0). This antibody can be used to localize S-100A and S-100B in various tissue sections. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S-100 protein, albeit non-uniformly. A large number of well-differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell-derived tumors express S-100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S-100 protein.
Formulation	0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Host	Mouse
Immunogen Region	Purified bovine brain S100 protein (4C4.9) and recombinant full-length human protein (S100B/1012) were used as the immunogen for the S100 antibody cocktail.
Isotype	IgG2a,kappa
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No
Subcellular Location	Cytoplasmic, nuclear

Uniprot	P04271
Clone No	4C4.9 + S100B/1012

Concentration	0.2 mg/ml
Format	Purified
Purification	Protein G affinity chromatography
Storage	Store the S100B antibody cocktail at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Applications	IF, IHC-P
Dilution	Immunofluorescence: 1-2ug/ml,Immunohistochemistry (FFPE): 0.25-0.5ug/ml for 30 min at RT

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17113950-1	V3423-20UG	20ug	$219		Add to Cart
BHA17113950-2	V3423-100UG	100ug	$499		Add to Cart

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