Runx2 is a member of the RUNX family of transcription factors. It is a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. It can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Host
Rabbit
Immunogen Region
A portion of amino acids 1-30 from the human protein was used as the immunogen for this RUNX2 antibody.
Isotype
Rabbit Ig
Species Reactivity
Human
Note
The stated application concentrations are suggested starting amounts. Titration of the RUNX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Uniprot
Q13950
Format
Antigen affinity purified
Purity
Antigen affinity
Storage
Store at 4oC for up to one month. For long term, aliquot the RUNX2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.