Runx2 is a member of the RUNX family of transcription factors. It is a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. It can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Host
Rabbit
Immunogen Region
A portion of amino acids 1-30 from the human protein was used as the immunogen for this RUNX2 antibody.
Isotype
Ig
Predicted Reactivity
Human
Reactivity
Human
Recombinant
No
Uniprot
Q13950
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
Store at 4°C for up to one month. For long term, aliquot the RUNX2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.