The protein encoded by this gene contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. Alteatively spliced transcript variants encoding distinct isoforms have been reported.
Formulation
In ascites with 0.09% sodium azide
Host
Mouse
Immunogen Region
This RNF8 antibody was produced from mouse immunized with RNF8 recombinant protein.
Isotype
Mouse IgG1, k
Species Reactivity
Human
Note
Titration of the RNF8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Uniprot
O76064
Format
Ascites
Purity
Ascites
Storage
Aliquot the RNF8 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.