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Home / Primary Antibodies

RNF138 Antibody

SKU : BHA10558395

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA994526
Alternative Names	E3 ubiquitin-protein ligase RNF138; EC 6.3.2.-; RING finger protein 138; Nemo-like kinase-associated RING finger protein; NLK-associated RING finger protein
Categories	Primary Antibodies
Clonality	polyclonal
Description	E3 ubiquitin-protein ligase. Together with NLK, involved in the ubiquitination and degradation of TCF/LEF. Also exhibits auto-ubiquitination activity in combination with UBE2K. May act as a negative regulator in the Wnt/beta-catenin-mediated signaling pathway.Wang L., Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.Ota T., Nat. Genet. 36:40-45(2004).Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human RNF138.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	E3 ubiquitin-protein ligase. Together with NLK, involved in the ubiquitination and degradation of TCF/LEF. Also exhibits auto-ubiquitination activity in combination with UBE2K. May act as a negative regulator in the Wnt/beta-catenin-mediated signaling pathway. Wang L., Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases. Ota T., Nat. Genet. 36:40-45(2004). Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total RNF138 protein.
Subcellular Location	Chromosome

Uniprot	Q8WVD3
Database Links	HGNC:17765 OMIM:616319 KEGG:hsa:51444 STRING:9606.ENSP00000261593 UniGene:Hs.302408
Function	E3 ubiquitin-protein ligase involved in DNA damage response by promoting DNA resection and homologous recombination

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558395	CSB-PA994526	100ul	$297		Add to Cart

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