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Home / Primary Antibodies

RIOK3 Antibody

SKU : BHA10558671

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA570953
Alternative Names	EC 2.7.11.1; RIO kinase 3; sudD homolog;
Categories	Primary Antibodies
Clonality	polyclonal
Description	This gene was identified by the similarity of its product to the Aspergillus nidulans SUDD protein, an extragenic suppressor of the heat-sensitive bimD6 mutation that fails to attach properly to the spindle microtubules at a restrictive temperature. The specific function of this gene has not yet been determined.Anaya P., Gene 211:323-329(1998).Nusbaum C., Nature 437:551-555(2005).The MGC Project Team, Genome Res. 14:2121-2127(2004)
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human RIOK3.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	This gene was identified by the similarity of its product to the Aspergillus nidulans SUDD protein, an extragenic suppressor of the heat-sensitive bimD6 mutation that fails to attach properly to the spindle microtubules at a restrictive temperature. The specific function of this gene has not yet been determined. Anaya P., Gene 211:323-329(1998). Nusbaum C., Nature 437:551-555(2005). The MGC Project Team, Genome Res. 14:2121-2127(2004)
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total RIOK3 protein.
Subcellular Location	Cytoplasm

Uniprot	O14730
Database Links	HGNC:11451 OMIM:603579 KEGG:hsa:8780 STRING:9606.ENSP00000341874 UniGene:Hs.445511
Function	Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. May act as an adapter protein essential for the recruitment of TBK1 to IRF3
Protein Families	Protein kinase superfamily, RIO-type Ser/Thr kinase family
Tissue Specificity	Widely expressed.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558671	CSB-PA570953	100ul	$297		Add to Cart

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