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Home / Antibodies

RHOD Antibody

SKU : BHA10558652

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA945646
Alternative Names	Rho-related GTP-binding protein RhoD; Rho-related protein HP1; RhoHP1; RHOD;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton. Participates in reorganization of actin cytoskeleton By similarity.Shimizu F., Biochim. Biophys. Acta 1351:13-16(1997).Puhl H.L. III, Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.Taylor T.D., Nature 440:497-500(2006).Gasman S., Nat. Cell Biol. 5:195-204(2003).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human RHOD.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton. Participates in reorganization of actin cytoskeleton By similarity. Shimizu F., Biochim. Biophys. Acta 1351:13-16(1997). Puhl H.L. III, Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. Taylor T.D., Nature 440:497-500(2006). Gasman S., Nat. Cell Biol. 5:195-204(2003).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total RHOD protein.
Subcellular Location	Cell membrane, Lipid-anchor, Cytoplasmic side, Early endosome

Uniprot	O00212
Database Links	HGNC:670 OMIM:605781 KEGG:hsa:29984 STRING:9606.ENSP00000308576 UniGene:Hs.15114
Function	Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Participates in the reorganization of actin cytoskeleton; the function seems to involve WHAMM and includes regulation of filopodia formation and actin filament bundling. Can modulate the effect of DAPK3 in reorganization of actin cytoskeleton and focal adhesion dissolution.
Protein Families	Small GTPase superfamily, Rho family
Tissue Specificity	Heart, placenta, liver, skeletal muscle, and pancreas and, with weaker intensity, in several other tissues.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558652	CSB-PA945646	100ul	$297		Add to Cart

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