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Home / Primary Antibodies

RGS12 Antibody

SKU : BHA10558636

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA694009
Alternative Names	regulator of G-protein signaling 12;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. soform 5:Behaves as a cell cycle-dependent transcriptional repressor, promoting inhibition of S-phase DNA synthesis.Chatterjee T.K., J. Biol. Chem. 275:29660-29671(2000).Snow B.E., J. Biol. Chem. 273:17749-17755(1998).Hillier L.W., Nature 434:724-731(2005).
Host	Rabbit
Immunogen	Synthesized peptide derived from N-terminal of Human RGS12.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. soform 5:Behaves as a cell cycle-dependent transcriptional repressor, promoting inhibition of S-phase DNA synthesis. Chatterjee T.K., J. Biol. Chem. 275:29660-29671(2000). Snow B.E., J. Biol. Chem. 273:17749-17755(1998). Hillier L.W., Nature 434:724-731(2005).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total RGS12 protein.
Subcellular Location	Nucleus, Cytoplasm, Cell projection, dendrite, Cell junction, synapse, SUBCELLULAR LOCATION: Isoform 5: Nucleus matrix

Uniprot	O14924
Database Links	HGNC:9994 OMIM:602512 KEGG:hsa:6002 STRING:9606.ENSP00000339381 UniGene:Hs.527061
Function	Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form.
Tissue Specificity	Isoform 3 is brain specific.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558636	CSB-PA694009	100ul	$297		Add to Cart

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