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Home / Antibodies

RGS10 Antibody

SKU : BHA10558635

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA939703
Alternative Names	Regulator of G-protein signaling 10; RGS10;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Associates specifically with the activated forms of the G protein subunits G(i)-alpha and G(z)-alpha but fails to interact with the structurally and functionally distinct G(s)-alpha subunit. Activity on G(z)-alpha is inhibited by palmitoylation of the G-protein.Hunt T.W., Nature 383:175-177(1996).Chatterjee T.K., J. Biol. Chem. 275:24013-24021(2000).Burgon P.G., J. Biol. Chem. 276:32828-32834(2001).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human RGS10.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Associates specifically with the activated forms of the G protein subunits G(i)-alpha and G(z)-alpha but fails to interact with the structurally and functionally distinct G(s)-alpha subunit. Activity on G(z)-alpha is inhibited by palmitoylation of the G-protein. Hunt T.W., Nature 383:175-177(1996). Chatterjee T.K., J. Biol. Chem. 275:24013-24021(2000). Burgon P.G., J. Biol. Chem. 276:32828-32834(2001).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total RGS10 protein.
Subcellular Location	Cytoplasm, cytosol, Nucleus

Uniprot	O43665
Database Links	HGNC:9992 OMIM:602856 KEGG:hsa:6001 STRING:9606.ENSP00000358099 UniGene:Hs.501200
Function	Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the muscarinic acetylcholine receptor CHRM2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558635	CSB-PA939703	100ul	$297		Add to Cart

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