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Home / Primary Antibodies

RFC2 Antibody

SKU : BHA10558843

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA108812
Alternative Names	Replication factor C subunit 2; Activator 1 subunit 2; Replication factor C 40 kDa subunit; RF-C 40 kDa subunit; RFC40
Categories	Primary Antibodies
Clonality	polyclonal
Description	The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit binds ATP By similarity.Chen M., Proc. Natl. Acad. Sci. U.S.A. 89:2516-2520(1992).Hurwitz J., Submitted (SEP-1996) to the EMBL/GenBank/DDBJ databases.Martindale D.W., Mamm. Genome 11:890-898(2000).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human RFC2.
Involvement In Disease	RFC2 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region (PubMed:11003705).
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit binds ATP By similarity. Chen M., Proc. Natl. Acad. Sci. U.S.A. 89:2516-2520(1992). Hurwitz J., Submitted (SEP-1996) to the EMBL/GenBank/DDBJ databases. Martindale D.W., Mamm. Genome 11:890-898(2000).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total RFC2 protein.
Subcellular Location	Nucleus

Uniprot	P35250
Database Links	HGNC:9970 OMIM:194050 KEGG:hsa:5982 STRING:9606.ENSP00000055077 UniGene:Hs.647062
Function	The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit binds ATP (By similarity).
Pathway	DNA repair pathway
Protein Families	Activator 1 small subunits family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558843	CSB-PA108812	100ul	$297		Add to Cart

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