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Home / Antibodies

Retinol Binding Protein 4 Antibody / RBP4 (V8705SAF)

SKU : BHA17127716

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NSJ Bioreagents

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Mfr.No.	V8705SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	Retinol (Vitamin A) is transported in the blood bound to its carrier protein, retinol-binding protein (RBP), also designated plasma retinol-binding protein (PRBP) or RBP4. A member of the lipocalin family, RBP conveys retinol from stores in the liver to peripheral tissues. In plasma, RBP binds transthyretin (TTR, formerly called prealbumin) to prevent glomerular filtration of low molecular weight RBP in the kidneys. The stability of this complex holds diagnostic importance because the molar ratio of RBP:TTR provides an indirect way to indicate marginal Vitamin A deficiency. Vitamin A deficiency blocks the secretion of RBP, resulting in defective delivery and supply to epidermal cells. Originally identified solely as a transporter protein, recent studies correlating increased levels of RBP expression in adipose tissue with Insulin resistance have generated research into the possible roles the protein may play in the pathogenesis of type 2 diabetes and obesity.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	A portion of amino acids 29-148 from the human protein was used as the immunogen for the RBP4 antibody.
Isotype	Mouse IgG2c, kappa
Species Reactivity	Human
Note	Optimal dilution of the RBP4 antibody should be determined by the researcher.

Uniprot	P02753

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the RBP4 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	IHC-P
Description	Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/rbp4-antibody-rbp4-4053-v8705" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17127716	V8705SAF-100UG	100 ug	$499		Add to Cart

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