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Home / Primary Antibodies

REC8 Antibody

SKU : BHA10558480

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA939960
Alternative Names	Meiotic recombination protein REC8 homolog; Cohesin Rec8p; REC8; REC8L1;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II By similarity.Parisi S., Mol. Cell. Biol. 19:3515-3528(1999).Ota T., Nat. Genet. 36:40-45(2004).Ebert L., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human REC8.
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II By similarity. Parisi S., Mol. Cell. Biol. 19:3515-3528(1999). Ota T., Nat. Genet. 36:40-45(2004). Ebert L., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total REC8 protein.
Subcellular Location	Nucleus, Chromosome, Chromosome, centromere

Uniprot	O95072
Database Links	HGNC:16879 OMIM:608193 KEGG:hsa:9985 STRING:9606.ENSP00000308699 UniGene:Hs.419259
Function	Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II (By similarity).
Protein Families	Rad21 family
Tissue Specificity	Expressed in testis and thymus. Expressed in the B-cell lines WI-L2-NS and Namalwa (at protein level).

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558480	CSB-PA939960	100ul	$297		Add to Cart

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