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Home / Primary Antibodies

RAPGEF5 Antibody

SKU : BHA10558619

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA905052
Alternative Names	GFR; guanine nucleotide exchange factor for Rap1; M-Ras-regulated GEF; M-Ras-regulated Rap GEF; MR-GEF
Categories	Primary Antibodies
Clonality	polyclonal
Description	Guanine nucleotide exchange factor (GEF) for RAP1A, RAP2A and MRAS/M-Ras-GTP. Its association with MRAS inhibits Rap1 activation.Nagase T., DNA Res. 3:321-329(1996).Scherer S.W., Science 300:767-772(2003).Ichiba T., FEBS Lett. 457:85-89(1999)
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human RAPGEF5.
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Guanine nucleotide exchange factor (GEF) for RAP1A, RAP2A and MRAS/M-Ras-GTP. Its association with MRAS inhibits Rap1 activation. Nagase T., DNA Res. 3:321-329(1996). Scherer S.W., Science 300:767-772(2003). Ichiba T., FEBS Lett. 457:85-89(1999)
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total RAPGEF5 protein.
Subcellular Location	Nucleus

Uniprot	Q92565
Database Links	HGNC:16862 OMIM:609527 KEGG:hsa:9771 STRING:9606.ENSP00000343656 UniGene:Hs.174768
Function	Guanine nucleotide exchange factor (GEF) for RAP1A, RAP2A and MRAS/M-Ras-GTP. Its association with MRAS inhibits Rap1 activation.
Pathway	Ras signaling pathway Rap1 signaling pathway
Tissue Specificity	Widely expressed with highest levels in brain.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558619	CSB-PA905052	100ul	$297		Add to Cart

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