KIAA0474; RAP1 GTPase activating protein; Rap1 GTPase-activating protein 1; RAP1; GTPase activating protein 1
Categories
Primary Antibodies
Clonality
polyclonal
Description
GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state.Rubinfeld B., Cell 65:1033-1042(1991).Seki N., DNA Res. 4:345-349(1997).Gregory S.G., Nature 441:315-321(2006).
Host
Rabbit
Immunogen
Synthesized peptide derived from C-terminal of Human RAP1GDS1.
Raised In
Rabbit
Reactivity
Human, Mouse
Regulatory
RUO
Relevance
GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state.
GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state.
Pathway
Rap1 signaling pathway
Tissue Specificity
Significant expression seen in the brain, kidney and pancreas. Abundant in the cerebral cortex and expressed at much lower levels in the spinal cord. Not detected in the lymphoid tissues.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.