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Home / Antibodies

Rad21 Antibody (RQ4748)

SKU : BHA17109525

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NSJ Bioreagents

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Mfr.No.	RQ4748
Clonality	Monoclonal
Description	Double-strand-break repair protein rad21 homolog' is a cleavable component of the cohesin complex, involved in chromosome cohesion during cell cycle, in DNA repair, and in apoptosis. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition, this protein is cleaved by separase/ESPL1 and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Also plays a role in apoptosis, via its cleavage by caspase-3/CASP3 or caspase-7/CASP7 during early steps of apoptosis: the C-terminal 64 kDa cleavage product may act as a nuclear signal to initiate cytoplasmic events involved in the apoptotic pathway. (UniProt)
Formulation	Antibody in PBS with 0.02% sodium azide and 50% glycerol
Host	Rabbit
Immunogen Region	A synthetic peptide specific to human Rad21 was used as the immunogen for the Rad21 antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	O60216
Clone No	CBH-18

Format	Purified
Purification	Affinity purified
Storage	Store the Rad21 antibody at -20°C.

Applications	WB
Dilution	Weste blot: 1:500-1:1000

Product Manual	Data Sheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA17109525	RQ4748	100ul	$419		Add to Cart

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