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Home / Primary Antibodies

RAD18 Antibody

SKU : BHA10558394

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA274794
Alternative Names	E3 ubiquitin-protein ligase RAD18; hHR18; hRAD18; postreplication repair protein hRAD18p; Postreplication repair protein RAD18
Categories	Primary Antibodies
Clonality	polyclonal
Description	E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity.Tateishi S., Proc. Natl. Acad. Sci. U.S.A. 97:7927-7932(2000).Xin H., Nucleic Acids Res. 28:2847-2854(2000).Muzny D.M., Nature 440:1194-1198(2006).
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human RAD18.
Raised In	Rabbit
Reactivity	Human, Rat
Regulatory	RUO
Relevance	E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity. Tateishi S., Proc. Natl. Acad. Sci. U.S.A. 97:7927-7932(2000). Xin H., Nucleic Acids Res. 28:2847-2854(2000). Muzny D.M., Nature 440:1194-1198(2006).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total RAD18 protein.
Subcellular Location	Nucleus, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome

Uniprot	Q9NS91
Database Links	HGNC:18278 OMIM:605256 KEGG:hsa:56852 STRING:9606.ENSP00000264926 UniGene:Hs.375684
Function	E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity.
Protein Families	RAD18 family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558394	CSB-PA274794	100ul	$297		Add to Cart

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