Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes. Plays a key role in eye and brain development and neurodegeneration.Chikri M.M., Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.Schaefer U., FEBS Lett. 466:148-154(2000).Cui W.C., Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human RAB18.
Involvement In Disease
Warburg micro syndrome 3 (WARBM3)
Raised In
Rabbit
Reactivity
Human, Mouse
Regulatory
RUO
Relevance
Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes. Plays a key role in eye and brain development and neurodegeneration.
Chikri M.M., Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases. Schaefer U., FEBS Lett. 466:148-154(2000). Cui W.C., Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total RAB18 protein.
Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes. Plays a key role in eye and brain development and neurodegeneration.
Protein Families
Small GTPase superfamily, Rab family
Tissue Specificity
Ubiquitous.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.