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Home / Primary Antibodies

Pyruvate Kinase Antibody / PKM2 (F54017)

SKU : BHA17119916

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NSJ Bioreagents

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Mfr.No.	F54017-0.1ML
Clonality	Monoclonal (mouse origin)
Description	Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival. (UniProt)
Formulation	Antibody in PBS with 50% Glycerol and 0.03% ProClin 300
Host	Mouse
Immunogen Region	A human recombinant partial protein was used as the immunogen for this PKM2 antibody.
Isotype	Mouse IgG1
Species Reactivity	Human, Mouse, Rat, Primate
Note	The stated application concentrations are suggested starting points. Titration of the PKM2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Uniprot	P14618

Format	Purified
Purity	Protein G affinity
Storage	Store the PKM2 antibody at -20oC.

Applications	WB, ICC/IF
Description	Weste blot: 1:1000,ICC/Immunofluorescence: 1:400

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17119916	F54017-0.1ML	0.1 ml	$379		Add to Cart

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