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Home / Primary Antibodies

Purified Anti-Human CD279/PD-1 Antibody[J116]

SKU : BHA10325775

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	E-AB-F1129A
Background	Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 (B7-H1) and PD-L2 (B7-DC) are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
Host	Mouse
Immunogen	0
Isotype	Mouse IgG1, kappa
Reactivity	Human

Clone No	J116
Research Area	Cancer, Cell Biology, Immunology

Buffer	PBS with 0.05% Proclin300
Concentration	0.2 mg/mL
Storage	Store at 2~8°C. Do not freeze.

Applications	FCM, IHC, IP

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA10325775	E-AB-F1129A	50?g	$45		Add to Cart
BHA10325775	E-AB-F1129A	100?g	$68		Add to Cart

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