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Home / Primary Antibodies

PTRF Antibody

SKU : BHA10558788

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA841086
Alternative Names	CAVIN; Cavin-1; CGL4; FKSG13; FLJ90031
Categories	Primary Antibodies
Clonality	polyclonal
Description	Plays an important role in caveolae formation and organization. Required for the sequestration of mobile caveolin into immobile caveolae. Termination of transcription by RNA polymerase I involves pausing of transcription by TTF1, and the dissociation of the transcription complex, releasing pre-rRNA and RNA polymerase I from the template. PTRF is required for dissociation of the ternary transcription complex.Wang Y.-G., Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.Jansa P., EMBO J. 17:2855-2864(1998).Aboulaich N., Biochem. J. 383:237-248(2004).
Host	Rabbit
Immunogen	Synthesized peptide derived from Internal of Human PTRF.
Involvement In Disease	Congenital generalized lipodystrophy 4 (CGL4)
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Plays an important role in caveolae formation and organization. Required for the sequestration of mobile caveolin into immobile caveolae. Termination of transcription by RNA polymerase I involves pausing of transcription by TTF1, and the dissociation of the transcription complex, releasing pre-rRNA and RNA polymerase I from the template. PTRF is required for dissociation of the ternary transcription complex. Wang Y.-G., Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases. Jansa P., EMBO J. 17:2855-2864(1998). Aboulaich N., Biochem. J. 383:237-248(2004).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total PTRF protein.
Subcellular Location	Membrane, caveola, Cell membrane, Microsome, Endoplasmic reticulum, Cytoplasm, cytosol, Mitochondrion, Nucleus

Uniprot	Q6NZI2
Database Links	HGNC:9688 OMIM:603198 KEGG:hsa:284119 STRING:9606.ENSP00000349541 UniGene:Hs.437191
Function	Plays an important role in caveolae formation and organization. Essential for the formation of caveolae in all tissues
Protein Families	CAVIN family

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10558788	CSB-PA841086	100ul	$297		Add to Cart

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