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Home / Primary Antibodies

PTPN22 Antibody / Protein tyrosine phosphatase non-receptor type 22 (RQ6794)

SKU : BHA17119207

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NSJ Bioreagents

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Mfr.No.	RQ6794
Cellular Localization	nuclear, cell membrane, Cytoplasmic
Clonality	Polyclonal (rabbit origin)
Description	Protein tyrosine phosphatase, non-receptor type 22 (lymphoid), also known as PTPN22, is a protein that in humans is encoded by the PTPN22 gene. It is mapped to 1p13.2. This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alteatively spliced transcript variants encoding distinct isoforms have been described.
Host	Rabbit
Immunogen Region	Recombinant human protein (amino acids M1-K42) was used as the immunogen for the PTPN22 antibody.
Isotype	Rabbit IgG
Reactivity	Human, Rat
Recombinant	No

Uniprot	Q9Y2R2

Buffer	Lyophilized from 1X PBS with 2% Trehalose
Concentration	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format	Antigen affinity purified
Purification	Antigen affinity purified
Storage	After reconstitution, the PTPN22 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Applications	WB, IF, Direct ELISA
Dilution	Weste blot: 1-2ug/ml,Immunofluorescence (FFPE): 5ug/ml,Direct ELISA: 0.1-0.5ug/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA17119207	RQ6794	100ug	$419		Add to Cart

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